The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical presentation, etiology, epidemiology, molecular biology, classification, and staging are all discussed. Clear guidance is provided on diagnosis and differential diagnosis, and treatment strategies are explained in detail, including administration of hematopoietic growth factors, biologically based treatment, hematopoietic stem cell transplantation, and supportive care. Additional chapter is devoted to MDS in children. This practically oriented book will be of value to a broad spectrum of students and practitioners in the field.
Trapped in her seventeeth-century past, a brilliant writer exacts an ancient revenge in the twentieth... A child wanders, lost and alone, in the maze of New York... A lottery ticket turns up a winning combination of love and death...
In the turbulent period between 1870 and 1930, the contours on modernity were taking shape, especially the connections between technology, politics, and aesthetics. The trilogy The Nihilist Order traces the genealogy of the nihilist-totalitarian syndrome. The Futurist Syndrome, the third volume of the trilogy, deals with three variants of the avant-garde artistic movements of European Futurism and their fascination with totalitarian regimes. These movements, represented here by their leaders, are: Italian Futurism and fascism, represented by Marinetti; Russian Cubo-Futurism and bolshevism, represented by Mayakovsky; and English Vorticism and its glorification of Hitler, represented by Wyndham Lewis. The Italian futurist movement typified the double image of modernism. Worshipping the major features of the modern age such as dynamism, speed, and industrial and urban aesthetics, they added ideological concepts such as ´´heroic technology´´ and ´´mechanized warfare.´´ The Russian version of F
This comprehensive monograph on paraneoplastic syndromes discusses the clinical symptomatology, the diagnosis, the associated autoantibodies and the treatment of individual paraneoplastic syndromes. It emphasizes both the clinical experience of the office and provides an extensive review of the literature.
Metabolic syndrome as an important risk factor for stroke, Alzheimer disease, and depression presents readers with cutting edge and comprehensive information on relationship among metabolic syndrome, stroke, Alzheimer disease, and depression. It is hoped that this monograph will be useful to postgraduate students, faculty, research scientists, pharmacologists, nutritionists, and physicians, who are curious about the molecular mechanisms that link metabolic syndrome with stroke, Alzheimer disease, and depression.
Mit Alien Syndrome erscheint ein rasantes Action-Rollenspiel vor der Kulisse eines ideenreichen Sci-Fi-Universums für den Sony PSP. Zwei neue Action-Rollenspiel-Modi, eine dramatische Einzelspieler-Kampagne und ein Multiplayer-Kooperationsmodus für bis zu vier Spieler, sorgen für explosive Abenteuer-Spannung. Alien Syndrome für PSP basiert auf der klassischen SEGA-Lizenz und versetzt die Fans in ein intuitiv zugängliches Action-Rollenspiel, das gleichzeitig jede Menge Tiefe bietet und mit zahlreichen Features und Missionen herausfordert. Den Spieler erwarten 20 verschiedene Waffen, von Flammenwerfern und Vierlauflasern über Nanobot-Schwärme, die ihre Feinde auflösen, bis hin zu Brandgranaten, die Feuergeysire aus dem Boden speien lassen. Mit der riesigen Vielfalt an Waffen und Fähigkeiten ist fast jede nur erdenkliche Kampfstrategie möglich, um die Horden von mehr als 100 verschiedenen Alien-Feinden zu bezwingen.
Since the first edition was published in 2003, an enormous amount of research into Asperger Syndrome (AS) and autism spectrum disorders has been conducted. New genetic and epigenetic theories, updated findings on viable therapies, and targeted skill-building programs provide a solid foundation of information for professionals to use in practice and impart to concerned families. The Second Edition of Asperger Syndrome synthesizes the current state of the field, beginning with the controversy over the proposed linking of the condition with autism in the DSM-5. This comprehensive guide gives readers a deeper understanding of the disorder, detailing the effective strategies and therapies available to improve the lives of young people with AS and ensure their successful transition from childhood to adolescence to adulthood. Focusing on core deficit and treatment areas, expert contributors analyze the evidence base on behavioral and pharmacological interventions as well as educational strategies geared toward bolstering cognitive and social skills. In addition to epidemiology, etiology, diagnosis, and assessment, this volume offers the most current information on: Counseling and other therapeutic strategies for children with AS and their families. Early intervention for children and youth with AS. Social skills instruction for children with AS. Evaluating evidence-based instruction for children with AS. Comprehensive education-based mental health services for students diagnosed on the autism spectrum. Practical advice for families, from a parent of a child with AS. The Second Edition of Asperger Syndrome is an essential reference for researchers, clinicians, and scientist-practitioners in clinical child, school, and developmental psychology; child and adolescent psychiatry; education; rehabilitation medicine/therapy; social work; and pediatrics.
Down syndrome is a genetic condition which causes varying degrees of learning disability as well as other health problems. Nearly one baby in every 1000 born in the UK has the condition. Parents are often frightened and confused by the birth of a baby with Down syndrome, and they need reassurance as well as up-to-date information regarding the condition. The new edition of this highly regarded book for parents of children with Down syndrome covers a number of important new developments in research and clinical practice that have occurred in the field in recent years. These include several newly recognised medical conditions that are known to occur more commonly in patients with Down syndrome, for example, glaucoma, gastrointestinal malformations, feeding difficulties, gastro-oesophageal reflux, coeliac disease, and diabetes. This expanded edition also includes new recommendations regarding routine health checks in line with those of the UK Down Syndrome Medical Interest Group (UKDSMIG). Additionally the book covers new prenatal screening methods which have been developed to identify Down syndrome during pregnancy.
Progeria (also known as ´´Hutchinson-Gilford progeria syndrome´´ and ´´Hutchinson-Gilford syndrome´´) is an extremely rare, severe, genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The disease has a very low incidence and occurs in one per eight million live births.Those born with progeria typically live about thirteen years, although many have been known to live into their late teens and early twenties and rare individuals may even reach their forties. It is a genetic condition that occurs as a new mutation and is not usually inherited, although there is a uniquely inheritable form. This is in contrast to another rare but similar premature aging syndrome, dyskeratosis congenita (DKC), which is inheritable and will often be expressed multiple times in a family line.
The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a uniform and systematic basis to present the latest evidence-based research, including the basic science of APS, task force reports from the Congress on controversial aspects of APS, and future directions of APS research. This book will appeal to all clinicians involved in the treatment and management of APS patients, to residents in a variety of medical subspecialties, and to research scientists interested in a better understanding of this complex and evolving disease.